Suppose I grant that pigs and dogs are self-aware to some degree, and do have thoughts about things in the future. That would provide some reason for thinking it intrinsically wrong to kill them - not absolutely wrong, but perhaps quite a serious wrong. Still, there are other animals - chickens maybe, or fish - who can feel pain but don't have any self-awareness or capacity for thinking about the future. For those animals, you haven't given me any reason why painless killing would be wrong, if other animals take their place and lead an equally good life.
Peter SingerThere is an obvious evolutionary explanation for the scarcity of altruistic saints: Without a strong predilection for their own interests, our ancestors would have been unlikely to survive, reproduce, and give their own offspring a chance of doing the same. Now conditions have changed and for most of us, surviving and reproducing isn't such a struggle but we still carry the genes of our ancestors and they influence - not determine, but influence - our behavior.
Peter SingerAt present scientists do not look for alternatives simply because they do not care enough about the animals they are using.
Peter Singer