Secrets are hard but solvable problems and we should talk about them. It's hard to work toward a radically better future if you don't believe in secrets.

In the '30s, the Keynesian stuff worked at least in the sense that you could print money without inflation because there was all this productivity growth happening. That's not going to work today.

I think anything that requires real global breakthroughs requires a degree of intensity and sustained effort that cannot be done part time, so it's something you have to do around the clock, and that doesn't compute with our existing educational system.

But the indeterminate future is somehow one in which probability and statistics are the dominant modality for making sense of the world. Bell curves and random walks define what the future is going to look like. The standard pedagogical argument is that high schools should get rid of calculus and replace it with statistics, which is really important and actually useful. There has been a powerful shift toward the idea that statistical ways of thinking are going to drive the future.

When you are starting a new business you don't want to go after giant markets. You want to go after small markets and take over those markets quickly.

You want to be the last company in a category. Those are the ones that are really valuable.

The lowest-hanging fruit in preventative medicine is just to really focus on nutrition.