By the time a student gets to college, he's spent a decade curating a bewilderingly diverse résumé to prepare for a completely unknowable future. Come what may, he's ready-for nothing in particular.

The most successful businesses have an idea for the future that's very different from the present.

When you are starting a new business you don't want to go after giant markets. You want to go after small markets and take over those markets quickly.

Twitter is hard to evaluate. They have a lot of potential. It's a horribly mismanaged company — probably a lot of pot-smoking going on there. But it's such a solid franchise it may even work with all that.

Moving first is a tactic, not a goal.

A company does better the less it pays the CEO.

I'm always very excited about trying to do something on next-generation biotechnology and life sciences because I think if we can cure cancer or dementia, we can really make the future a lot better and I think these things are eminently doable.