It may be said "In research, if you know what you are doing, then you shouldn't be doing it." In a sense, if the answer turns out to be exactly what you expected, then you have learned nothing new, although you may have had your confidence increased somewhat.

If the prior distribution, at which I am frankly guessing, has little or no effect on the result, then why bother; and if it has a large effect, then since I do not know what I am doing how would I dare act on the conclusions drawn?

Mathematics is an interesting intellectual sport but it should not be allowed to stand in the way of obtaining sensible information about physical processes.

One of the characteristics of successful scientists is having courage. Once you get your courage up and believe that you can do important problems, then you can. If you think you can't, almost surely you are not going to.

Science is concerned with what is possible while engineering is concerned with choosing, from among the many possible ways, one that meets a number of often poorly stated economic and practical objectives.

It may be said "In research, if you know what you are doing, then you shouldn't be doing it." In a sense, if the answer turns out to be exactly what you expected, then you have learned nothing new, although you may have had your confidence increased somewhat.

The real problem is what can man and machine do together and not in competition.