What are the important problems of your field?

Often the great scientists, by turning the problem around a bit, changed a defect to an asset. For example, many scientists when they found they couldn't do a problem finally began to study why not. They then turned it around the other way and said, "But of course, this is what it is" and got an important result.

If you don't work on important problems, it's not likely that you'll do important work.

The most dangerous thought you can have as a creative person is to think you know what you’re doing.

Science is composed of laws which were originally based on a small, carefully selected set of observations, often not very accurately measured originally; but the laws have later been found to apply over much wider ranges of observations and much more accurately than the original data justified.

Perhaps the central problem we face in all of computer science is how we are to get to the situation where we build on top of the work of others rather than redoing so much of it in a trivially different way.

A parable: A man was examining the construction of a cathedral. He asked a stone mason what he was doing chipping the stones, and the mason replied, "I am making stones." He asked a stone carver what he was doing. "I am carving a gargoyle." And so it went, each person said in detail what they were doing. Finally he came to an old woman who was sweeping the ground. She said. "I am helping build a cathedral." ...Most of the time each person is immersed in the details of one special part of the whole and does not think of how what they are doing relates to the larger picture.