In its efforts to learn as much as possible about nature, modern physics has found that certain things can never be "known" with certainty. Much of our knowledge must always remain uncertain. The most we can know is in terms of probabilities.
Richard P. FeynmanThe difficulty really is psychological and exists in the perpetual torment that results from your saying to yourself, "But how can it be like that?" which is a reflection of uncontrolled but utterly vain desire to see it in terms of something familiar. ... If you will simply admit that maybe Nature does behave like this, you will find her a delightful, entrancing thing. Do not keep saying to yourself, if you can possible avoid it, "But how can it be like that?" because you will get 'down the drain', into a blind alley from which nobody has escaped. Nobody knows how it can be like that.
Richard P. FeynmanPhilosophy of science is about as useful to scientists as ornithology is to birds.
Richard P. Feynman