I’ve never agreed with the conventional wisdom that ‘actors are great liars.’ If more people understood the acting process, the goals of good actors, the conventional wisdom would be ‘actors are terrible liars,’ because only bad actors lie on the job. The good ones hate fakery and avoid manufactured emotion at all costs. Any script is enough of a lie anyway. (What experience does any actor have with flying a spacecraft? Killing someone?) What’s called for, what actors are hired for, is to bring reality to the arbitrary.

There was a period in my life where I went out a lot and I had a really good time. But that period is over.

It's the media that take an isolated incident and make it a deciding factor in a presidential campaign, as opposed to the real issues, like abortion, the homeless, the deficit. The same is true with actors and their lifestyles.

I am getting on in years, and I have a very extensive IMDB page, and I cannot keep track of my own credits.

I have never felt at any point in my life, good or bad, any ill will ever from the man or woman on the street.

I remember Tucker Toomey was named so because "T's are funny!" And if Garry Marshall says it's funny, by god, it must be so.

All the shows we did pre-airdate, and I'd come out - "Rob Lowe!" - and it was [Offers bored applause.] After the show aired? I came out - "Rob Lowe!" - and the place was, like, bedlam. And then the next week, they wouldn't let anyone under the age of 20 into the audience. And I'm going, "So that's how it works! Okay!"