The universe works in mysterious ways and for me it worked out perfectly. With all respect to everybody else, Aaron Sorkin is and was The West Wing, full stop. There's no West Wing without him.

[Jim Belushi] and I have a great thing going, and a really weird, offbeat story. [Living In Peril] is the type of movie that I don't even know if it would be made today. Just a very odd film. But a very fun movie.

['John F. Kennedy] movie is based on a massive best-selling book, which is always helpful. And then the script was amazing and answered my question, "Why this? Why now?" And the "why now" is that it's 50 years since the assassination, and the country needs to have and will have a conversation about that. And the "why this" is the construct, which I think is sort of ingenious.

I know, there are so many great lines [in Tommy Boy]. People say to me, "Did you eat paint chips for a living?" Or, "These shoes are worth more than your life." And the one I get all the time is, "Brothers don't shake hands, brothers gotta hug!"

That's what I grew up loving. Whether it's 30 Rock or The Office or Parks And Rec... I don't know if those still work on network today or not, but The Grinder did not. But the great news is that it lives on on Netflix.

If people find me attractive, it would be for reasons that anybody finds anybody attractive. It's something that comes from within, and it manifests itself physically.

All the shows we did pre-airdate, and I'd come out - "Rob Lowe!" - and it was [Offers bored applause.] After the show aired? I came out - "Rob Lowe!" - and the place was, like, bedlam. And then the next week, they wouldn't let anyone under the age of 20 into the audience. And I'm going, "So that's how it works! Okay!"