If somebody else is achieving more than I am, that means I can do it, too. Everybody has the ability to raise themselves up, and my life has been marked by that.

[J.F.Kennedy] is an iconic figure. And to make it even worse, he's a hero of mine. And every actor will tell you that you can't play heroes. And you can't play villains. You can only play human beings.

It was a role [Dean Sanderson] I hadn't seen before, and yet it was very accessible and relatable at the same time. I read scripts that have one or the other, but I rarely read scripts that have both. And it was laugh-out-loud funny.

I enjoy experiencing life. Being a celebrity can really stand in the way of that.

Sam Seaborn is the best character that's ever been written for me, certainly. By far. And it's a timeless show [The West Wing], one that's having another resurgence now, with people so in an uproar politically.

I’ve never agreed with the conventional wisdom that ‘actors are great liars.’ If more people understood the acting process, the goals of good actors, the conventional wisdom would be ‘actors are terrible liars,’ because only bad actors lie on the job. The good ones hate fakery and avoid manufactured emotion at all costs. Any script is enough of a lie anyway. (What experience does any actor have with flying a spacecraft? Killing someone?) What’s called for, what actors are hired for, is to bring reality to the arbitrary.

All the shows we did pre-airdate, and I'd come out - "Rob Lowe!" - and it was [Offers bored applause.] After the show aired? I came out - "Rob Lowe!" - and the place was, like, bedlam. And then the next week, they wouldn't let anyone under the age of 20 into the audience. And I'm going, "So that's how it works! Okay!"