I don't look back with any bitterness, though there are a couple of judgment calls and some '80s hairdos that I'd like to do over.

All the shows we did pre-airdate, and I'd come out - "Rob Lowe!" - and it was [Offers bored applause.] After the show aired? I came out - "Rob Lowe!" - and the place was, like, bedlam. And then the next week, they wouldn't let anyone under the age of 20 into the audience. And I'm going, "So that's how it works! Okay!"

When I was a teen idol, I was so goddamn pretty I wouldn't have taken myself seriously.

[J.F.Kennedy] is an iconic figure. And to make it even worse, he's a hero of mine. And every actor will tell you that you can't play heroes. And you can't play villains. You can only play human beings.

I think it was Alfred Hitchcock who said 90 percent of successful moviemaking is in the casting. The same is true in life. Who you are exposed to, who you choose to surround yourself with, is a unique variable in all of our experiences and it is hugely important in making us who we are. Seek out interesting characters, tough adversaries and strong mentors and your life can be rich, textured, highly entertaining and successful, like a Best Picture winner. Surround yourself with dullards, people of vanilla safety and unextraordinary ease, and you may find your life going straight to DVD.

It was a role [Dean Sanderson] I hadn't seen before, and yet it was very accessible and relatable at the same time. I read scripts that have one or the other, but I rarely read scripts that have both. And it was laugh-out-loud funny.

Intelligence is that aspect of human cognition that we haven't managed to emulate yet.