Good science requires distinguishing between "felt knowledge" and knowledge arising out of testable observations. "I am sure" is a mental sensation, not a testable conclusion. Put hunches, gut feelings, and intuitions into the suggestion box. Let empiric methods shake out the good from bad suggestions.

Good science is more than the mechanics of research and experimentation. Good science requires that scientists look inward-to contemplate the origin of their thoughts. The failures of science do not begin with flawed evidence or fumbled statistics; they begin with personal self-deception and an unjustified sense of knowing.

Certainty and similar states of ‘knowing what we know’ arise out of involuntary brain mechanisms that, like love or anger, function independently of reason.

Good science requires distinguishing between "felt knowledge" and knowledge arising out of testable observations. "I am sure" is a mental sensation, not a testable conclusion. Put hunches, gut feelings, and intuitions into the suggestion box. Let empiric methods shake out the good from bad suggestions.

Temperance is a bridle of gold; he, who uses it rightly, is more like a god than a man.

Every schoolboy hath that famous testament of Grunnius Corocotta Porcellus at his fingers end.

Naught so sweet as melancholy.