Finish this lecture, go outside, and unexpectedly get gored by an elephant, and you are going to secrete glucocorticoids. There's no way out of it. You cannot psychologically reframe your experience and decide you did not like the shirt, here's an excuse to throw it out - that sort of thing.
Robert M. SapolskyDepression is not generalized pessimism, but pessimism specific to the effects of one's own skilled action.
Robert M. SapolskyPerhaps most excitingly, we are uncovering the brain basis of our behaviors - normal, abnormal and in-between. We are mapping a neurobiology of what makes us us.
Robert M. SapolskyThe frontal cortex is an incredibly interesting part of the brain - ours is proportionately bigger and/or more complex than in any other species.
Robert M. SapolskyStress is not a state of mind... it's measurable and dangerous, and humans can't seem to find their off-switch.
Robert M. SapolskyPulling a gun's trigger can be an appalling act. But if it is suicidal drawing fire to save someone, it has an utterly different meaning. Placing your hand on someone's arm can be an act of deep compassion or the first step of betrayal. The punch line? It's all about context, and the biology of context is vastly more complicated than the biology of the behavior itself.
Robert M. Sapolsky