I think that good parenting should allow children to be children. That naivety and slightly open way of looking at the world is very valuable.

We live longer and healthier lives than ever before. Animal research has improved the treatment of infections, helped with immunisation, improved cancer treatment and had a big impact on managing heart disease, brain disorders, arthritis and transplantation.

When I look in the mirror, I am slightly reminded of self-portraits by Durer and by Rembrandt, because they both show a degree of introspection. I see some element of disappointment; I see a sense of humour, but also something that is faintly ridiculous; and I see somebody who is frightened of being found out and thought lightweight.

I don't believe in regretting - one should try to move on. My mum was good at that. She was deeply in love with my father, and he died when I was nine. She remarried, and her second husband died, too. I saw the grieving process she went through. My mother had this way of moving on. It was a fine trait.

I went to school with butterflies of fear every day for years - from primary school onwards - not just worried about being bullied by classmates, but by teachers.

It's extraordinary to think that if you walked into a room and said you had never heard of Hamlet, you would be regarded as a Philistine. But you could walk into the same room and say, 'I don't know what a proton is,' and people would just laugh and say, 'Why should you know?'

Following 25 children for the TV series 'Child of Our Time' has been extraordinary. The BBC's original plan was to commemorate the new millennium. What better way than to film a number of expectant mums from across the U.K.? Coming from widely different backgrounds, all were due to give birth on January 1, 2000.