There can be a science to joke writing, there are certainly rules and patterns that can be followed, but I think most of the best comedy goes beyond the rules.

Science is very cross-generational; you're not just aiming it at twentysomethings, or eightysomethings. Every town's got a really broad selection of people and age groups interested in science.

If the Royal Variety Show was put in a matter transportation machine with the Royal Institution Christmas lectures, this is what you'd get.

I have a very vibrant imposter syndrome that goes on throughout most of my life, but nothing more than when someone has to put a hat on me or some kind of sash and go, 'We're giving you this certificate.'

I have spent a reasonable percentage of my life in libraries - I like the hush.

My wife could turn to me and she may say, 'Why do you love me?' And I can with all honesty look her in the eye and say, 'Because our pheromones matched our olfactory receptors.'

Not since Jimmy Carr have I seen a cold computer programme on stage generate so much laughter.