Not since Jimmy Carr have I seen a cold computer programme on stage generate so much laughter.

If the Royal Variety Show was put in a matter transportation machine with the Royal Institution Christmas lectures, this is what you'd get.

You always need to find the balance in the science, but the balance to talking about evolutionary theory is not to talk about creationism, that's not a balance, that's misleading and it's just wrong.

I'm glad the universe is pointless. It means if I get to the end of my life, the universe can't turn to me and go, 'What have you been doing, you idiot? That's not the point!

Homeopaths do not have a physical brain, but merely 'skull water' with the memory of brains.

Not since Jimmy Carr have I seen a cold computer programme on stage generate so much laughter.

I am not man or beast; I am bibliosexual, and a seedy bibliosexual who haunts the streets, laden with carrier bags held by blistered fingers, stooping under the weight of the rucksack that has brought on sciatica and a Dickensian demeanour.