It was Darwin's chief contribution, not only to Biology but to the whole of natural science, to have brought to light a process by which contingencies a priori improbable, are given, in the process of time, an increasing probability, until it is their non-occurrence rather than their occurrence which becomes highly improbable.
Ronald FisherWe have usually no knowledge that any one factor will exert its effects independently of all others that can be varied, or that its effects are particularly simply related to variations in these other factors.
Ronald FisherThe more highly adapted an organism becomes, the less adaptable it is to any new change.
Ronald FisherThe best causes tend to attract to their support the worst arguments, which seems to be equally true in the intellectual and in the moral sense.
Ronald Fisher