The neutral zone of selective advantage in the neighbourhood of zero is thus so narrow that changes in the environment, and in the genetic constitution of species, must cause this zone to be crossed and perhaps recrossed relatively rapidly in the course of evolutionary change, so that many possible gene substitutions may have a fluctuating history of advance and regression before the final balance of selective advantage is determined.
Ronald FisherThe best causes tend to attract to their support the worst arguments, which seems to be equally true in the intellectual and in the moral sense.
Ronald FisherI believe sanity and realism can be restored to the teaching of Mathematical Statistics most easily and directly by entrusting such teaching largely to men and women who have had personal experience of research in the Natural Sciences.
Ronald FisherWe have usually no knowledge that any one factor will exert its effects independently of all others that can be varied, or that its effects are particularly simply related to variations in these other factors.
Ronald FisherExperimental observations are only experience carefully planned in advance, and designed to form a secure basis of new knowledge.
Ronald FisherNatural Selection is not Evolution. Yet, ever since the two words have been in common use, the theory of Natural Selection has been employed as a convenient abbreviation for the theory of Evolution by means of Natural Selection, put forward by Darwin and Wallace. This has had the unfortunate consequence that the theory of Natural Selection itself has scarcely ever, if ever, received separate consideration.
Ronald FisherWe can set no limit to human potentialities; all that is best in man can be bettered; it is not a question of producing a highly efficient machine, ... but of quickening all the distinctly human features, all that is best in man, all the different qualities, some obvious, some infinitely subtle, which we recognize as humanly excellent.
Ronald Fisher