I did a lot of theater when I was in high school and college. I also did stand-up in college, so it was always part of what I did.

I'm big on the importance of science, particularly right now at this point in time when there's sort of a systematic rejection of science by a lot of people in America.

The success of The Simpsons really opened doors. It showed that if you were working in animation you didn't necessarily have to be working in kids' television.

There were two things that became apparent, pretty quickly into the process. One was that the muscles didn't take as much reconditioning as I thought they would. It was more like voice acting than I thought it would be. You're using your whole body and there are things that are different, but when you are doing a character, even in the booth, nobody is watching but my face will do different things when I do different characters.

If I were to do a musical, I think I would rather make a film musical.

I'm the guy in the crowd making fun of the hero's shirt.

I can't believe I am hosting the Oscars. It's an honor everyone else said no.