There were two things that became apparent, pretty quickly into the process. One was that the muscles didn't take as much reconditioning as I thought they would. It was more like voice acting than I thought it would be. You're using your whole body and there are things that are different, but when you are doing a character, even in the booth, nobody is watching but my face will do different things when I do different characters.

The worst thing to happen at the Oscars would be if nothing happened. You want something unscripted, something to riff on, something kinda out there.

There are people on staff who have made that point, that the upside to a second Bush term is that it makes 'American Dad' work better. To me, the price is too high. I would gladly give up the comedy to have a President Kerry. But you work with what you have.

I did a lot of theater when I was in high school and college. I also did stand-up in college, so it was always part of what I did.

The Simpsons are ugly-looking, and they should be. That's what works. That's one of the things that's funny.

Fox is notorious for having a very thick skin about taking shots at themselves.

There have to be people who are vocal about the advancement of knowledge over faith.