Shutting people down creatively often doesn't get the best performance out of them.

Alzheimer's is a family disease...It requires countless hours of care, which are typically provided by family caregivers...Wi thout professional help, it can be impossible to juggle providing that care with jobs, raising kids or just time for yourself.

To me Arthur and James Bond aren't the same because they both drink. So I would kind of equate it to that. They're different guys who both have a similar habit. To me they're very different guys though.

It was amazing how much their [Seth Rogen, Evan Goldberg, Shauna Robertson] process seemed familiar to me, translating that into the work that I had done and giving actors a lot of freedom and doing a lot of improvisation and a total respect and collaboration with all the department heads and all the crews, and just really making it an enjoyable industry rather than just clocking in and doing a job which a lot of movies are.

I think around that time I met David [Gordon Green] or, well, we all met at Superbad and Judd [Apatow] said, 'I'm thinking about having him direct [ Knocked Up].' Sounded like a good idea.

I'd moved to L.A., and everyone's actors here and writers, they were like super emotional and super in touch with their feelings, and it seemed like every two weeks one of my friend just coming to me and, like, you hurt my feelings the other day, dude.

We originally actually wrote Franco's part [in the Pineapple Express] for me and the part I ultimately played just for someone else in general. Then when we got Franco involved we thought it was a good idea to switch the roles. I think it worked really well.