The No. 1 impediment to women succeeding in the workforce is now in the home.

I'd worked on leprosy and malaria in India [at the World Bank] and asked myself the question: Why do we let 2 million children die every year around the world for not having clean water? Because they're faceless and nameless. So, for me, Facebook looked like it was going to solve the problem of the invisible victim.

Every job will demand some sacrifice. The key is to avoid unnecessary sacrifice.

Both men and women react negatively when women negotiate on their own behalf. A man can just negotiate: "I have a better offer. That's not enough to make my family's ends meet." No one feels bad about it. But when a woman does that, there's a backlash.

You know, there has never been a 24-hour period in five years when I have not responded to e-mail at Facebook. I am not saying it's easy. I work long hours.

Our aspirations are really for women to be in half the leadership roles and men to be doing half the work of parenting.

When the man is traveling with a man, he says, "Let's stay up late and work on this and get this to be better." When the man's traveling with the woman, for the sake of appearances he doesn't do the work with her. That's a lost opportunity for her to be a success.