Nobody got anything great by playing it safe.

At some point, you have to make a decision. Boundaries don't keep other people out. They fence you in. Life is messy. That's how we're made. So, you can waste your lives drawing lines. Or you can live your life crossing them

I never, ever pay attention to the ratings. I stopped paying attention to the ratings somewhere around season two or three of Grey's. It's something I have no control over, so I don't even pay attention.

My parents created a world in which the only ­barrier to your success is your own imagination.

There is no longer one way to consume TV. Some shows you want to watch live, some shows you only discover through streaming, some shows you just feel you need to DVR.

I want my daughters to see me and know me as a woman who works. I want that example set for them... I am a better mother for it. The woman I am because I get to run Shondaland, because I get write all day, because I get to spend my days making things up, that woman is a better person - and a better mother. Because that woman is happy. That woman is fulfilled. That woman is whole. I wouldn't want them to know the me who didn't get to do this all day long. I wouldn't want them to know the me who wasn't doing.

Everyone always says to me, 'Why aren't there more people of color on television?' I'm like, 'Why don't you ask a bunch of people who aren't putting people of color on television why there aren't more people of color on television?'