The origin of the conflict, frustration, and anxiety we experience does not lie in the nature of the world itself but in our distorted conceptions of the world.

The Four Noble Truths are pragmatic rather than dogmatic. They suggest a course of action to be followed rather than a set of dogmas to be believed. The four truths are prescriptions for behavior rather than descriptions of reality. The Buddha compares himself to a doctor who offers a course of therapeutic treatment to heal one’s ills. To embark on such a therapy is not designed to bring one any closer to ‘the Truth’ but to enable one’s life to flourish here and now, hopefully leaving a legacy that will continue to have beneficial repercussions after one’s death. (154)

So the Buddha is presenting awakening not as a single mystical experience that may come upon us at some meditation, some private moment of transcendence, but rather as a new engagement with life. He is offering us a relationship to the world that is more sensitized to suffering and the causes of suffering, and he gives rise to the possibility of another kind of culture, another kind of civilization.

The problem with certainty is that it is static; it can do little but endlessly reassert itself. Uncertainty, by contrast, is full of unknowns, possibilities, and risks.

This deep agnosticism is more than the refusal of conventional agnosticism to take a stand on whether God exists or whether the mind survives bodily death. It is the willingness to embrace the fundamental bewilderment of a finite, fallible creature as the basis for leading a life that no longer clings to the superficial consolations of certainty.

Each time the dharma moved into a different civilization or historical period, it faced a twofold challenge: to maintain its integrity as an internally coherent tradition, and to express its vision in a way that responded to the needs of the new situation.

Living from our deepest understanding requires an enormous effort, especially when it goes against the stream of our instinctually programmed perceptions of the world.