The initial configuration of the universe may have been chosen by God, or it may itself have been determined by the laws of science. In either case, it would seem that everything in the universe would then be determined by evolution according to the laws of science, so it is difficult to see how we can be masters of our fate.

There is no unique picture of reality.

We only have to look at ourselves to see how intelligent life might develop into something we wouldnt want to meet. I imagine they might exist in massive ships, having used up all the resources from their home planet. Such advanced aliens would perhaps become nomads, looking to conquer and colonize whatever planets they can reach.

Science makes God unnecessary.

Then we shall... be able to take part in the discussion of the question of why it is that we and the universe exist. If we find the answer to that, it would be the ultimate triumph of human reason - for then we would know the mind of God.

Any physical theory is always provisional, in the sense that it is only a hypothesis: you can never prove it. No matter how many times the results of experiments agree with some theory, you can never be sure that the next time the result will not contradict the theory.

It's clearly possible for a something to acquire higher intelligence than its ancestors: we evolved to be smarter than our ape-like ancestors, and Einstein was smarter than his parents.