Americans are hungry for change both at home and in our relations with the rest of the world.

There is not an inherent contradiction between a Ukraine that has longstanding historic and cultural ties to Russia, and a modern Ukraine that wants to integrate more closely with Europe.

If we are to garner sustained U.S. domestic support for future trade agreements, we have to make sure those Americans who have suffered as a consequence of past agreements have an effective social safety net, adjustment assistance, opportunities for retraining and new job creation that enables all Americans to thrive.

We're well aware, and we have been for a long time, that there is a real threat from adversaries, state actors, non-state actors, to hack us, influence us, destroy stuff through cyber means. Because cyber threat has been understood for a while, it's longstanding, it's a concern.

I don't get drunk, I get a little happy on rare occasion, and I'm probably dancing if I'm that happy.

We must be honest in acknowledging that neither Germany nor the US has the luxury of assuming that we can skate by on half-measures in Afghanistan and Pakistan and not risk suffering the consequences.

In this day and age, the U.S. and Europe do not have the luxury of focusing solely on a single region.