You have to have a somewhat cold heart to be a writer.

Whatever we call it - mind, character, soul - we like to think we possess something that is greater than the sum of our neurons and that animates us.

It's a long way from not having enough serotonin to thinking the world is "stale, flat and unprofitable"; even further to writing a play about a man driven by that thought.

It is easy to slip into a parallel universe. There are so many of them: worlds of the insane, the criminal, the crippled, the dying, perhaps of the dead as well. These worlds exist alongside this world and resemble it, but are not in it.

Are you crazy? It's a common phrase, I know. But it means something particular to me: the tunnels, the security screens, the plastic forks, the shimmering, ever-shifting borderline that like all boundaries beckons and asks to be crossed. I do not want to cross it again.

In a strange way we were free. We'd reached the end of the line. We had nothing more to lose. Our privacy, our liberty, our dignity: all of this was gone and we were stripped down to the bare bones of our selves

Don't separate the mind from the body. Don't separate even character - you can't. Our unit of existence is a body, a physical, tangible, sensate entity with perceptions and reactions that express it and form it simultaneously. Disease is one of our languages. Doctors understand what disease has to say about itself. It's up to the person with the disease to understand what the disease has to say to her.