While we've made progress with our numbers, this will be a harder-to-reach group, and we have less money to do it.... Many people don't know or understand about the tax credit that they can receive. And so affordability is a barrier. We know that a disproportionate number of those who are still uninsured are young.

Can we have a conversation about the substance? That's what I welcome. We're happy to have those conversations if there are places where people think there can be improvements. We want competition in the system, so let's talk about that.

I have been fortunate to work in places where people have a passion for their work. At HHS the passion sort of exceeds passion - it's a vocation.... I obviously knew that there were certainly some challenges that I would be taking on both with the work and the politics. [But] I probably did not have the right expectation level with regard to the number and volume of crises that would occur.

As a global community, we must ensure that legitimate concerns about liability do not hold back the possibility of developing an Ebola vaccine, an essential strategy in our global response to the Ebola epidemic in West Africa.

While natural disasters capture headlines and national attention short-term, the work of recovery and rebuilding is long-term.

We know there are states, like Alaska, where there are not a lot of providers. How do we work on issues like that? How do we work on making sure that the small-business part of this works better?... And if people have [alternate] plans, let's compare them and see. Access, affordability, and quality - that's what this is about. [But] "repeal" is a symbol of something that I don't think is connected to the substance of what's happening. Do you want to take away care from people who have preexisting conditions? [Repeal] takes you backward.

My mom didn't run for mayor until she was 65 years old - it was like a second and third career.... The way I've always thought about it is that I don't believe you run for office because you want a job. I believe if you run for office, it's because you have a vision for change. And if I ever came to that point, that's what would lead [me to run]. And right now I'm happily in a position where I believe I can work to deliver impact and work for change.