To date, the enterprise of thinking has moved us radically away from understanding anything.

Safety is really a concern of mine, and what I've been telling people recently is that until there's animal and human data on a drug it should probably be looked at very carefully.

If you go to Paris you know more about reality than people who don't. If you smoke DMT you know more about reality than people who don't.

We are living in a very pivotal time. The time that we inherit from science is a time to humble you, to dwarf you. It tells you that the sun will not fluxuate for another billion years, that species come and go, and, in other words, on a temporal scale you don't matter. And that now doesn't matter. But when you look at the release of energy, the asymptotic speeding up of processes, we tend to be xenophobically oriented toward the human.

It is the people who are 'far out' who are gaining advantage in the evolutionary jostling for efficacious strategies.

And what is the primary datum? It's the felt presence of immediate experience. In other words, being here now is the primary datum.

The sine qua non for obtaining a psychedelic experience is humbling yourself to the point where you admit that you must submit to the experience of the plant or the drug. This act of surrender is the major technical function you will be called upon to perform during the psychedelic trip.