It is not what we believe, but why we believe it. Moral responsibility lies in diligently weighing the evidence. We must actively doubt; we have to scrutinize our views, not take them on trust. No virtue attached to blindly accepting orthodoxy, however 'venerable'.

Try to learn something about everything and everything about something.

As for your doctrines I am prepared to go to the Stake if requisite ... I trust you will not allow yourself to be in any way disgusted or annoyed by the considerable abuse & misrepresentation which unless I greatly mistake is in store for you... And as to the curs which will bark and yelp - you must recollect that some of your friends at any rate are endowed with an amount of combativeness which (though you have often & justly rebuked it) may stand you in good stead - I am sharpening up my claws and beak in readiness.

It is the first duty of a hypothesis to be intelligible.

The secret of genius is to carry the spirit of childhood into maturity.

No delusion is greater than the notion that method and industry can make up for lack of mother-wit, either in science or in practical life.

When I reached intellectual maturity and began to ask myself whether I was an atheist, a theist, or a pantheist; a materialist, or an idealist; a Christian, or a freethinker; I found that the more I learned and reflected, the less ready was the answer; until, at last, I came to the conclusion that I had neither art nor part with any of these denominations, except the last.