I hated tobacco. I could have almost lent my support to any institution that had for its object the putting of tobacco smokers to death...I now feel that smoking in moderation is a comfortable and laudable practice, and is productive of good. There is no more harm in a pipe than in a cup of tea. You may poison yourself by drinking too much green tea, and kill yourself by eating too many beefsteaks. For my part, I consider that tobacco, in moderation, is a sweetener and equalizer of the temper.

Misery is a match that never goes out.

The medieval university looked backwards; it professed to be a storehouse of old knowledge. The modern university looks forward, and is a factory of new knowledge.

In matters of the intellect, do not pretend that conclusions are certain which are not demonstrated or demonstrable. That I take to be the agnostic faith, which if a man keep whole and undefiled, he shall not be ashamed to look the universe in the face, whatever the future may have in store for him.

I have no faith, very little hope, and as much charity as I can afford.

Only a scientific people can survive in a scientific future.

If the hypothesis of evolution is true, living matter must have arisen from non-living matter; for by the hypothesis the condition of the globe was at one time such, that living matter could not have existed in it, life being entirely incompatible with the gaseous state.