Agnosticism, in fact, is not a creed, but a method, the essence of which lies in the rigorous application of a single principle. ... Positively the principle may be expressed: In matters of the intellect, follow your reason as far as it will take you, without regard to any other consideration. And negatively: In matters of the intellect, do not pretend that conclusions are certain which are not demonstrated or demonstrable.

The great tragedy of science - the slaying of a beautiful hypothesis by an ugly fact.

Living things have no inertia, and tend to no equilibrium.

And you very soon find out, if you have not found it out before, that patience and tenacity of purpose are worth more than twice their weight of cleverness.

From the dawn of exact knowledge to the present day, observation, experiment, and speculation have gone hand in hand; and, whenever science has halted or strayed from the right path, it has been, either because its votaries have been content with mere unverified or unverifiable speculation (and this is the commonest case, because observation and experiment are hard work, while speculation is amusing); or it has been, because the accumulation of details of observation has for a time excluded speculation.

God give me strength to face a fact though it slay me.

The student of Nature wonders the more and is astonished the less, the more conversant he becomes with her operations; but of all the perennial miracles she offers to his inspection, perhaps the most worthy of admiration is the development of a plant or of an animal from its embryo.