All significant breakthroughs are break -“withs” old ways of thinking.

What chemists took from Dalton was not new experimental laws but a new way of practicing chemistry (he himself called it the 'new system of chemical philosophy'), and this proved so rapidly fruitful that only a few of the older chemists in France and Britain were able to resist it.

History, if viewed as a repository for more than anecdote or chronology, could produce a decisive transformation in the image of science by which we are now possessed.

Individuals who break through by inventing a new paradigm are almost always either very young men or very new to the field whose paradigm they change. These are the men who, being little committed by prior practice to the traditional rules of normal science, are particularly likely to see that those rules no longer define a playable game and conceive another set that can replace them.

Far from being magisterial in its objectivity, science was conditioned by history, society, and the prejudices of scientists.

The transition between competing paradigms cannot be made a step at a time, forced by logic and neutral experience. Like the gestalt switch, it must occur all at once (though not necessarily in an instant) or not at all.

Normal science, the activity in which most scientists inevitably spend most all their time, is predicated on the assumption that the scientific community knows what the world is like. Normal science often suppresses fundamental novelties because they are necessarily subversive of its basic commitments.