Different is better when it is more effective or more fun.

People feel personally slighted if you don't respond to them in 30 seconds and treat email as instant messenger.

A recession is very bad for publicly traded companies, but it's the best time for startups. When you have massive layoffs, there's more competition for available jobs, which means that an entrepreneur can hire freelancers at a lower cost.

The brain is where most people really screw up.

Creating demand is hard. Filling demand is easier. Don't create a product, then seek someone to sell it to. Find a market - define your customers - then find or develop a product for them.

Companies that start by redesigning the economics of an industry often finish by redesigning the whole industry-and owning it.

The downstream effects are unknown. Do your best and hope for the best. If you're improving the world-however you define that-consider your job well done.