Imagine the world of mobile based on Nokia and Motorola if Apple had not been restarted by a missionary entrepreneur named Steve Jobs who cared more for his vision than being tactical and financial.

I'm not a political person. I'm a techie nerd, and I enjoy the techie part. I mean, all my life, I've loved great technology.

I'm a fiscal hawk. I vote against all taxes, but I do believe the environment, and climate change, is a bigger issue than fiscal deficits are as a risk to the nation.

In the next 10 years, data science and software will do more for medicine than all of the biological sciences together.

As for companies invested in the space - I think its important to distinguish between a good investment and a material climate change technology - you can have the first without the second, even in the "clean tech" space.

No one will pay you to solve a non-problem.

Startups allow technologists and scientists to take risks and change plans in a way that would be frowned upon in a big company. Having said that, big companies will play a key role in certain areas and in partnerships with little companies. Each has its strengths.