I believe, along with many others, that you must first ask for what you want before you can have it.
Be clear about what you want to accomplish, and whether the circumstances surrounding you are actively helping you toward the goal.
I lost a company. So what? It's just stuff. Can't take it with you.
Nothing is an obstacle unless you say it is.
Commitment is the match that lights the fire.
You may not be responsible for getting knocked down. But you're certainly responsible for getting back up.