The good news is we are seeing an incredible surge in non-animal technologies in laboratories. With researchers using stem cells, visually impaired people may one day have new corneas and lenses grown from their own cells. That is likely to be a more effective and cheaper approach than using animals.

People know what happened in California, and they know it can happen again and again. They know that no group has passed more ballot measures than we have. They know we have a focused strategy. They know we have a budget of $150 million a year. And they know we're ready for a fight.

People are being forced to confront the realities. At the same time, we have an ever-growing understanding of the intelligence and emotional capacities of animals and an acceptance of the principle that animal cruelty is a moral problem.

The response by agribusiness interests has been to back laws that ban animal advocates from taking pictures or videos at these facilities, and ban the media from publishing any that are taken. The laws also make it a crime for animal advocates to seek employment at animal enterprises without disclosing their intentions. Media coverage of the legislative fights is overwhelmingly negative for agriculture interests. The impression left among consumers is that the proponents had something to hide.

China is now urging citizens to eat less meat. Factory farming comes with immense costs to a society, and Chinese leaders are starting to recognize its implications for water use, the efficient use of grains and other food resources, and human health concerns.

The issue of xenotransplantation - such as transplanting animal organs into humans - is fraught with risks for animals, naturally, and for people.

Human creativity and innovation is going to make the exploitation of animals look not only inhumane but obsolete and cumbersome.