we each devise our means of escape from the intolerable.

Style comes only have long, hard practice and writing.

I felt a kind of numbness, an enervation, but more particularly an odd fragility - as if my body had actually become frail, hypersensitive and somehow disjointed and clumsy, lacking normal coordination. And soon I was in the throes of a pervasive hypochondria.

A disruption of the circadian cycle—the metabolic and glandular rhythms that are central to our workaday life—seems to be involved in many, if not most, cases of depression; this is why brutal insomnia so often occurs and is most likely why each day’s pattern of distress exhibits fairly predictable alternating periods of intensity and relief.

It is hopelessness even more than pain that crushes the soul.

Nonfiction writers are second-class citizens, the Ellis Island of literature. We just can't quite get in. And yes, it pisses me off.

I felt myself no longer a husk but a body with some of the body's sweet juices stirring again. I had my first dream in many months, confused but to this day imperishable, with a flute in it somewhere, and a wild goose, and a dancing girl.