You largely constructed your depression. It wasn't given to you. Therefore, you can deconstruct it.

If something is irrational, that means it won't work. It's usually unrealistic.

You never truly need what you want. That is the main and thoroughgoing key to serenity.

I would have liked having children to some degree, but frankly I haven't got the time to take the kids to the goddamn ballgame. So it would have had more disadvantages than advantages for them.

Let's suppose somebody abused you sexually. You still had a choice, though not a good one, about what to tell yourself about the abuse.

If I had been a member of the academic establishment, I could have done other experiments.

Freud had a gene for inefficiency, and I think I have a gene for efficiency.