The biggest handicap in research is an ability to think outside the box. The handicap is being encumbered by all the conventional wisdom in a given field.

The aim is to postpone frailty, postpone degenerative disease, debilitation and so on and thereby shorten the period at the end of life, which is passed in a decrepit or disabled state, while extending life as a whole.

The scientific method actually correctly uses the most direct evidence as the most reliable, because that's the way you are least likely to get led astray into dead ends and to misunderstand your data.

Ageing is, simply and clearly, the accumulation of damage in the body. That's all that ageing is.

Wikipedia was a big help for science, especially science communication, and it shows no sign of diminishing in importance.

There is no difference between saving lives and extending lives, because in both cases we are giving people the chance of more life.

Public enthusiasm for new advances is a key ingredient in influencing policy-makers to stimulate follow-up work with suitable funding, and it can be achieved far faster now that interested non-specialists can explore new research autonomously and can also be appealed to directly by scientists.