The biggest handicap in research is an ability to think outside the box. The handicap is being encumbered by all the conventional wisdom in a given field.

Ageing is, simply and clearly, the accumulation of damage in the body. That's all that ageing is.

Public enthusiasm for new advances is a key ingredient in influencing policy-makers to stimulate follow-up work with suitable funding, and it can be achieved far faster now that interested non-specialists can explore new research autonomously and can also be appealed to directly by scientists.

Basically, the body does have a vast amount of inbuilt anti-ageing machinery; it's just not 100% comprehensive, so it allows a small number of different types of molecular and cellular damage to happen and accumulate.

The scientific method actually correctly uses the most direct evidence as the most reliable, because that's the way you are least likely to get led astray into dead ends and to misunderstand your data.

I don't work on longevity, I work on keeping people healthy.

I dont often meet people who want to suffer cardiovascular disease or whatever, and we get those things as a result of the lifelong accumulation of various types of molecular and cellular damage.