The aim is to postpone frailty, postpone degenerative disease, debilitation and so on and thereby shorten the period at the end of life, which is passed in a decrepit or disabled state, while extending life as a whole.

Theres nothing wrong with making the best of ones declining years, but what does annoy me is the fatalism. Now that were seriously in range of finding therapies that actually work against ageing, this apathy, of course, becomes an enormous part of the problem.

I don't work on longevity, I work on keeping people healthy.

My approach is to start from the straightforward principle that our body is a machine. A very complicated machine, but none the less a machine, and it can be subjected to maintenance and repair in the same way as a simple machine, like a car.

I think it's reasonable to suppose that one could oscillate between being biologically 20 and biologically 25 indefinitely.

The biggest handicap in research is an ability to think outside the box. The handicap is being encumbered by all the conventional wisdom in a given field.

Most scientists will get serious media exposure about twice in their entire career. And they'll get that because they've actually done an experiment that was interesting.