The underlying struggle - between worlds of plenty and worlds of want; between the modern and the ancient; between those who embrace our teeming, colliding, irksome diversity, while still insisting on a set of values that binds us together, and those who would seek, under whatever flag or slogan or sacred text, a certainty and simplification that justifies cruelty toward those not like us.

Filibuster has long tradition, but used to harm civil rights.

I think that there's no doubt that as I see friends, families, children of gay couples who are thriving, you know, that has an impact on how I think about these issues.

I'm named Barack Hussein Obama. I'm African-­American.

Across the globe there are girls who will one day lead nations, if only we afford them the chance to choose their own destinies.

Like no other illness, AIDS tests our ability to put ourselves in someone else's shoes - to empathize with the plight of our fellow man. While most would agree that the AIDS orphan or the transfusion victim or the wronged wife contracted the disease through no fault of their own, it has too often been easy for some to point to the unfaithful husband or the promiscuous youth or the gay man and say This is your fault. You have sinned. I don't think that's a satisfactory response. My faith reminds me that we all are sinners.

Ironically, the single thing that has strengthened Iran over the last several years has been the war in Iraq. Iraq was Iran's mortal enemy. That was cleared away. And what we've seen over the last several years is Iran's influence grow. They have funded Hezbollah, they have funded Hamas, they have gone from zero centrifuges to 4,000 centrifuges to develop a nuclear weapon.