My only agenda for the next two years is the same as the one I’ve had since the day I swore an oath on the steps of this Capitol — to do what I believe is best for America.

I think we need missile defense. But I want to make sure it works, that it's cost effective, that the technologies are operable, that it's our best possible strategy, and that hasn't been shown.

The more we can encourage entrepreneurship, particularly for young people, the more they have hope. That requires some reforms in these [African] governments: rooting out corruption, increased transparency and how government operates, making sure that regulations are not designed just to advantage elites, but are allowing people who have a good idea to get out there and get things done.

It's important to know that the vast majority of people who were excited in 2008 are still really enthusiastic. We've got more volunteers now than ever, and they're engaged, they're motivated, they're not paying attention to the ups and downs of polls or Washington.

We don't really have any kind of regulatory structure at all.

Palestinians will never realize their independence by denying the right of Israel to exist.

Some may still deny the overwhelming judgment of science, but none can avoid the devastating impact of raging fires, and crippling drought, and more powerful storms.