Now is the time for all of us to take our share of responsibility for a global response to global challenges.

Shooting in Orlando is a sobering reminder that attacks on any American, regardless of race, ethnicity, religion or sexual orientation, is an attack on all of us and on the fundamental values of equality and dignity that define us as a country. And no act of hate or terror will ever change who we are or the values that make us Americans.

I think I'm able to reach a lot of folks, despite the fact that the conventional news media sometimes says, "You know, this speech is too long," or "It's too complicated," or "He needs to have better sound bites," or what have you.

We had to get out of Chicago so quick. Election night happens, suddenly I'm talking to Ben Bernanke and Hank Paulson and trying to figure out whether the world's going to fly apart, and Michelle is trying to figure out where the girls are going to go to school. And we pack up and leave and basically our house in Chicago just became like a time capsule. My desk in my home office still had stacks of articles and bills and stuff from 2008.

We know that ISIL and other terrorist groups are actively encouraging people, around the world and in our country, to commit terrible acts of violence, oftentimes as lone-wolf actors.

If you’re walking down the right path and you’re willing to keep walking, eventually you’ll make progress.

For the sake of our children and our future, we must do more to combat climate change. Now, it's true that no single event makes a trend. But the fact is the 12 hottest years on record have all come in the last 15. Heat waves, droughts, wildfires, floods-all are now more frequent and more intense. We can choose to believe that Superstorm Sandy, and the most severe drought in decades, and the worst wildfires some states have ever seen were all just a freak coincidence. Or we can choose to believe in the overwhelming judgment of science-and act before it's too late.