The information society should serve all of its citizens, not only the technically sophisticated and economically privileged.

Even for the diseases we don't focus on, cancer, heart disease, you're going to be way better off being sick 10 years from now than any time in the past.

To win big, you sometimes have to take big risks.

Although I don't have a prescription for what others should do, I know I have been very fortunate and feel a responsibility to give back to society in a very significant way.

When I was trying to figure out why lives have improved so much in the last 300 years, where we've gone from a third of kids dying before 5 to - by 1990 it was down to 10% - now it's down to 5%. And saying why, over all history, there were smart people, but that number didn't change. Average life span didn't change. What's magical about what's been deemed the Industrial Revolution? It's really energy intensity.

The spread of online information isn't just good for charities. It's also good for donors. You can go to a site like Charity Navigator, which evaluates nonprofits on their financial health as well as the amount of information they share about their work.

Business isn't that complicated. I wouldn't want to put it on my business card.