So not only are we saving lives now, we're creating the incentive for the breakthroughs that over the next generation will mean we can take AIDS, malaria and TB and bring those numbers dramatically down.

Until recently, over 98 percent of teachers just got one word of feedback: Satisfactory. If all my bridge coach ever told me was that I was 'satisfactory,' I would have no hope of ever getting better.

If I had a dollar for every time someone made fun of me in high school-oh wait, I do!

If success corrupts, I'm probably pretty corrupted by now.

Software is inherently complicated. If you say to somebody I want an airline reservation system, to really say what you want in terms of overbooking and fares, and different airlines communicating with each or schedule changes, it's immensely complex. And so you can't write a program that's any simpler than that full specification.

The intersection of law, politics, and technology is going to force a lot of good thinking.

Today, we take the risk of nuclear war quite seriously, climate change not so much and epidemics least of all. But no single country, not even the United States, is well prepared. And even if one country is doing the right things to protect itself, it has to be a global thing.