I believe it’s not only possible to eradicate malaria; I believe it’s necessary. Ultimately, the cost of controlling it endlessly is not sustainable. The only way to stop this disease is to end it forever.

Vaccination is one of the easiest things on the way to development. It's much easier than roads and a great education system. It's very basic. It's one of the first things you want to get right.

In the philanthropy game, you're going for different outcomes: saving childhood lives, having kids grow up - because they don't have malnutrition or disease - that they achieve their full potential. We take for Warren [Buffett] things that, because he's very intelligent about the world but doesn't get to go out in Africa and see what we see, we've taken and say to him where we stand and it's basically a very positive report that his gift has made a phenomenal difference.

When I was in my 40s, Microsoft was my primary activity.

Internet TV and the move to the digital approach is quite revolutionary. TV has historically has been a broadcast medium with everybody picking from a very finite number of channels.

Every three years, we have to go to the governments and say, okay, you know you're saving millions of lives and even though your budgets are tight, helping Africa avoid this disaster really is a priority.

Strategically, a major function of the CEO is to look for bad news and encourage the organization to respond to it. Employees must be encouraged to share bad news as much as good news.