I'm not big on to-do lists. Instead, I use e-mail and desktop folders and my online calendar. So when I walk up to my desk, I can focus on the e-mails I've flagged and check the folders that are monitoring particular projects and particular blogs.

India just went 3 years with no cases [of polio]. Pakistan is our toughest location right now because some parts of the Taliban have not allowed vaccinators to come in and have even attacked vaccinators. We are hopeful this will get resolved since no one wants their kid to be paralyzed. I spend a lot of time making sure the polio campaign is doing the best it can. We have great computer models that help guide our activities.

Software is inherently complicated. If you say to somebody I want an airline reservation system, to really say what you want in terms of overbooking and fares, and different airlines communicating with each or schedule changes, it's immensely complex. And so you can't write a program that's any simpler than that full specification.

The Chinese are clearly inculcating the idea that science is exciting and important, and that's why they, as a whole-they're graduating four times as many engineers as we are, and that's just happened over the last 20 years.

I am super lucky. I've been in the area where things have been changing and been part of the digital revolution, the magic of software, the internet, the computer, and now the cellphone... so it's been a great privilege.

Even for the very best programmers ah, sometimes you'll see someone else's program or somebody will come along and they'll show you what can be done in a simpler way.

I think when smallpox was eliminated, the whole world got pretty excited about that because it’s just such a dramatic success.