Never before in history has innovation offered promise of so much to so many in so short a time.

With world health, every life you save is a wonderful thing, so it's not this question of whether you solve it or you don't. The chance of completely solving the problems has long odds. But really, the thing is that you get to save the first child, the second child, the third child. You can just feel good about that.

Taking a look back, one big reqret is, I left Harvard with no real awareness of the awful inequities in the world. The appalling disparities of health and wealth and opportunity that condemned millions of people to the lives of despair. I learned a lot here at Harvard about new ideas and economics, and politics. I got great exposure to the advances being made in the sciences. But humanities greatest advances are not in its discoveries, but in how those discoveries are applied to reduce inequity.

Virtually every company will be going out and empowering their workers with a certain set of tools, and the big difference in how much value is received from that will be how much the company steps back and really thinks through their business processes, thinking through how their business can change, how their project management, their customer feedback, their planning cycles can be quite different than they ever were before.

Why do people benefit in inverse proportion to their need? Well, market incentives make that happen.

In the old generation, if one kid bought a PlayStation 2 and the other kid bought an Xbox, at his house you played PlayStation, at your house you played Xbox. Now that it's online, all those early buyers who... you want to play with, they've got their reputation online of who they are and how good they are at these games.

In American math classes, we teach a lot of concepts poorly over many years. In the Asian systems they teach you very few concepts very well over a few years.