Programs today get very fat; the enhancements tend to slow the program down because people put in special checks. When they want to add some feature, they’ll just stick in these checks without thinking about how they might slow the thing down.

Flipping burgers is not beneath your dignity. Your Grandparents had a different word for burger flipping - they called it opportunity.

There's no such thing as going to a soapbox and saying, 'The government's corrupt,' and not having the intelligence service see your face. In the digital world, that can be done.

I believe it’s not only possible to eradicate malaria; I believe it’s necessary. Ultimately, the cost of controlling it endlessly is not sustainable. The only way to stop this disease is to end it forever.

Vaccination is one of the easiest things on the way to development. It's much easier than roads and a great education system. It's very basic. It's one of the first things you want to get right.

But the improvements will happen faster and last longer if we can channel market forces, including innovation that's tailored to the needs of the poorest, to complement what governments and nonprofits do. We need a system that draws in innovators and businesses in a far better way than we do today.

[AIDS ] is not a short-term emergency but it is something that, just like smallpox was many decades ago, we should aim for complete eradication.