Software was the key element that would determine how useable and how broadly applicable the machine was.

I believe innovation is the most powerful force for change in the world.

The flatter the corporate hierarchy, the more likely it is that employees will communicate bad news and act upon it.

AIDS we're - most of these diseases - we are down from the peak. We're down about 40 per cent from the peak and if we got the right vaccines, which are at the early stage of discovering, then the numbers would come down very dramatically. So that's why we talk about it as an emergency.

I believe that if you show people the problems and you show them the solutions they will be moved to act.

Governments will always play a huge part in solving big problems. They set public policy and are uniquely able to provide the resources to make sure solutions reach everyone who needs them. They also fund basic research, which is a crucial component of the innovation that improves life for everyone.

President [George] Bush made the U.S. absolutely the leader, between its own PEPFAR, and it's been by far the biggest Global Fund donor. That's a legacy.